An observer comparison study to evaluate a machine learning model to quantify the infected pneumonia on lung CT images

Quantification of infected lung volume using computed tomography (CT) images can play a critical role in predicting the severity of pulmonary infectious disease. Manual segmentation of infected areas from several CT image slices, however, is not efficient and viable in clinical practice. To assist clinicians in overcoming this challenge, we developed a new method to automatically segment and quantify the percentage of the infected lung volume. First, we used a public dataset of 20 COVID-19 patients, which consists of manually annotated lung and infection masks, to train a new joint deep learning (DL) model for lung and infection segmentation. As for lung segmentation, a Mask-RCNN model was applied to the lung volume with a novel postprocessing technique. Following that, an ensemble model with a customized residual attention UNet model and feature pyramid network (FPN) models was employed for infection segmentation. Next, we assembled another set of 80 CT scans of Covid-19 patients. Two chest radiologists manually evaluated each CT scan and reported the infected lung volume percentage using a customized graphical user interface (GUI). The developed DL-model was also employed to process these CT images. Then, we compared the agreement between the radiologist (manual) and model-based (automated) percentages of diseased regions. Additionally, the GUI was used to let radiologists rate acceptance of the DL-model generated segmentation results. Analyzing the results demonstrate that the agreement between manual and automated segmentation is >95% in 28 testing cases. Furthermore, >53% of testing cases received the top assessment rating scores from two radiologists (between four-five- score). Thus, this study illustrates the feasibility of developing a DL-model based automated tool to effectively provide quantitative evaluation of infected lung regions to assist in improving the efficiency of radiologists in infection diagnosis. © COPYRIGHT SPIE. Downloading of the is permitted for personal use only.

Assessing the Effect of the U.S. Vaccination Program on the Coronavirus Positivity Rate With a Multivariate Framework.

The factors influencing the incidence of COVID-19, including the impact of the vaccination programs, have been studied in the literature. Most studies focus on one or two factors, without considering their interactions, which is not enough to assess a vaccination program in a statistically robust manner. We examine the impact of the U.S. vaccination program on the SARS-CoV-2 positivity rate while simultaneously considering a large number of factors involved in the spread of the virus and the feedbacks among them. We consider the effects of the following sets of factors: socioeconomic factors, public policy factors, environmental factors, and non-observable factors. A time series Error Correction Model (ECM) was used to estimate the impact of the vaccination program at the national level on the positivity rate. Additionally, state-level ECMs with panel data were combined with machine learning techniques to assess the impact of the program and identify relevant factors to build the best-fitting models. We find that the vaccination program reduced the virus positivity rate. However, the program was partially undermined by a feedback loop in which increased vaccination led to increased mobility. Although some external factors reduced the positivity rate, the emergence of new variants increased the positivity rate. The positivity rate was associated with several forces acting simultaneously in opposite directions such as the number of vaccine doses administered and mobility. The existence of complex interactions, between the factors studied, implies that there is a need to combine different public policies to strengthen the impact of the vaccination program.

Chinese Teachers' Methodological Adaptation during the COVID-19 Pandemic

This research describes the methodological adaptation carried out by teachers of Chinese as a foreign language in the context of emergency remote teaching context produced by the COVID-19 pandemic in Costa Rica in 2020. An exploratory qualitative approach was adopted which included the participation of eleven teachers who responded to an online questionnaire and participated in a focus group discussion. The results suggest that information and communication technologies played a major role in this methodological adaptation and that, thanks to their integration into the teaching staff's methodology, the continuity of teaching in their courses' four macrocompetences could be ensured. It was also found that, for the development of the four language skills, a very varied range of activities was used, and a greater participation of students in their learning was achieved. As a conclusion, it was confirmed that the adaptations led to a considerable increase in the working hours of Chinese teaching staff.

Impact of the Work Context in Icu Covid on the Mental Health of the Health Professional

The period of the pandemic resulted in high levels of physical and emotional exhaustion in health professionals, pointing out issues related to health and prevention of worker illness. this study aimed to verify how the mental health of health professionals was impact because of their work in a Covid ICU. this is a systematic review on the impact of the Covid ICU work environment on the mental health of the health professional. The literature search included articles indexed in PubMed, Web of Science, Scielo and Periodical CAPES and SCOPUS during the month of June 2021. The search strategy used the following descriptors: "COVID-19" AND "ICU" AND "Mental Health" AND "Healthcare Workers". the present study identified 37 articles after searches in the databases, among these, 06 articles were select. Worsening of mental health variables were identified in all studies, evidencing the psychological impact of ICU professionals in the face of the COVID-19 pandemic. the need was identified for actions aimed at professionals working in an intensive care unit in order to implement regular mental health care.

Allergological study in patients referred for adverse reactions to the SARS CoV2 vaccine: Our experience

Background: Adverse reaction's reported after COVID 19 vaccination had a negative impact on public opinion. These adverse reactions may be or may be not be mediated by hypersensibility reactions. The proper assesment and the manegament of adverse reactions are crucial in order to offer a safer inmunitation and also to reduce the misinformation and the growing rejection to COVID 19 vaccination. Objective(s): To describe clinical characteristics and the allergological study done in different patients who had an adverse event right after COVID 19 vaccine administration Method: Descriptive study in patients who have experienced an adverse event after one single dose of the SARS CoV2's vaccine. Sex, age, atopy, drug allergies, anaphylaxis reaction (according to EEACI), syntoms, timing, vaccine and dose are described on this study. Skin test were done in every patient (Prick-Test and intradermo reaction) with ARN vaccine samples (Pfizer and Moderna), Adenovirus vaccine extract (Astrazeneca) and a battery of excipients (Polietilenglicol, Polisorbato80 and Trometamol). Result(s): The study included 44 patients with an average of 48,76 +/- 12,23 years, (93% women-29% atopic). 29% of the patients reported to be allergic to other drugs (AINES especially). The most frequent reaction according to EEACI anaphilaxy's classification was Grade 1 with a 61%. Grade 2: 18%, Grade 3: 21%. Urticaria and/or angioedema were the most frequent syntoms (60%) followed by disnea (20%) and being late syntoms (50%) the most usual ones. Pfizer was the most implicated vaccine (64%) with the first dose (84%). Skin tests with Polietilenglicol, Trometamol and Polisorbato80 at different concentrations were negative in all patients but two, one positive to Polisorbato80 0.004mg/ml with a previous sensitization to Prontosan (contains Polisorbato) and another one positive to Trometamol 0.1mg/ml. Conclusion(s): Allergists play a main role to offer the maximum befenits to their patients and to improve the vaccine's safety. Skin tests were the most efective tool to diagnose hypersensibility reactions. The 93,17% of the patients with a negative test result tolerated the second dose. The others did not get the second dose due to their own will. Avoiding the COVID 19 vaccine was recommended in those patients with a hypersensibility to the vaccine components diagnose.

Monetary policy rate in Mexico due to the effects of Covid-19

The economic crisis feeded by Covid-19 has produced supply and demand shocks that affect the potential product and consumer preferences, an impact that suggests that the neutral real interest rate was modified and, therefore, the real interest rate should be adjusted so as not to generate a deeper economic contraction in Mexico. We estimate the value of the neutral rate using the Laubach and Williams method, based on the Kalman filter, and confirm the results with a cointegrated vector of autoregressions (CVAR) model. The results show that the neutral real rate, theoretically consistent with the full employment rate and the inflation target in Mexico, is reduced to 0.1 % and the nominal to 3.1 %. The empirical determination of the neutral rate based on two different methods for Mexico and its use to approximate how expansive the monetary policy should be in Mexico in the COVID stage. The results suggests the existence of enough room for an expansionary monetary policy that allows facing the crisis and boost economic activity for at least three years. © 2020 Instituto Mexicano de Ejecutivos de Finanzas. All rights reserved.

Trends in the Costa Rican urban real estate market in the young adult segment

The real estate system is leaving behind the restrictions and impact of the COVID-19 pandemic and is beginning to recover pre-pandemic sales levels. New real estate developments must consider the changing preferences of buyers. This study analyzed the preferences of the young adult segment. Data was collected with a digital questionnaire, distributed in the cantons of Belén and Heredia in the province of Heredia in Costa Rica. A total of 383 surveys met the inclusion criteria, 52.7% were from women, most were university students and salaried. 65% were interested in having their own home, with no significant statistical difference between horizontal or vertical housing, but 79% would prefer to have two or more rooms. 87.2% would prefer to have access to a supermarket, 50% access to a pharmacy and 27.2% to a veterinarian;90% prefer a home near their work and 96% prefers to have green and recreating spaces. Developers and entrepreneurs in the real estate market must consider these preferences when planning and offering real estate products. © 2022 Latin American and Caribbean Consortium of Engineering Institutions. All rights reserved.

PSYCHOMETRIC PROPERTIES OF THE COVID-19 BURNOUT SCALE IN BRAZIL

The present study aims to adapt and analyze the psychometric properties (evidence of factor validity and internal consistency) of the COVID-19 Burnout Scale in a sample of Brazilian health professionals. Two studies were carried out (N total = 427). In Study 1 [202 health professionals (age over 18), mainly women (82%) and psychologists (31.2%)], an exploratory factor analysis support the one-factor solution and the suitability of the ten items. Moreover, was also presented in Study 2 [225 health professionals (over 18 years old), the majority of women (79.6%) and psychologists (24.8%)] results of confirmatory factor analysis and item parameters (Item Response Theory) that corroborate the unifactorial structure and convergent validity with the Coronavirus Anxiety Scale. The results indicate that this measure may be suitable for use in research and in the burnout evaluation scenario. © 2022 Universidad Miguel Hernandez. All rights reserved.

Government decisions to contain the pandemic and its effects on world merchandise trade

The outbreak and rapid spread of the coronavirus (COVID-19) deepened the slowdown in international trade, as decisions taken by governments to contain the spread of the virus hurt economic activity by slowing production or even stopping it altogether. The objective of this article is to analyze the level of severity of the restrictive public health measures applied by governments to contain the COVID-19 pandemic and the effects of these decisions on world merchandise trade. The strictness index is used as an indicator of the severity of the measures applied by the countries, calculated daily based on the score of nine metrics, whose values range between 0 and 100;as well as the annual growth rates of world merchandise trade. The results reveal that most countries recorded the strictest and longest lockdowns when there were no vaccines, simultaneously experiencing sharp declines, to varying degrees, in their merchandise trade growth rates;In conclusion, it is observed that, as the vaccination campaigns progressed, the end of the confinement was closer, as was the recovery of economic-commercial activity and employment © 2023, Revista de Ciencias Sociales.All Rights Reserved.

Corporate Social Responsibility in Bolivia: Hospital Responses to the COVID-19 Pandemic

The coronavirus (COVID-19) pandemic has had an impact on Bolivia's state of health, economy, and social fabric. The world is grappling with the consequences of the COVID-19 pandemic on firms, workers, consumers, communities, and each other. As a result of these consequences, people all over the world are committed to working together and supporting one another in all possible ways. Using stakeholder theory and Corporate Social Responsibility (CSR), this study explores hospital responses to the COVID-19 pandemic in Bolivia from the perspectives of hospital managers, hospital staff, and patients. This study used quantitative and qualitative analyses to understand CSR initiatives, operational challenges, and health-care quality services in Bolivian hospitals during the COVID-19 pandemic. Based on the results, different recommendations are suggested. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Breast Cancer educational program in women who attend chemotherapy during the context of COVID-19 pandemic

Introduction: Breast cancer is the most important cause of cancer death in Mexico, so health literacy during the COVID-19 pandemic is very important to reduce morbidity and mortality. Objective: To evaluate the effectiveness and satisfaction of an educational oncology program during the COVID-19 pandemic. Material and methods: Quasi-experimental study pre-post educational intervention (brief educational program), in 31 patients who underwent chemotherapy during the pandemic between April and July 2021, including COVID-19 education, therapeutic education in breast cancer and health promotion recommendations. Health literacy was analyzed using the Wilcoxon rank test for related samples. Results: The Wilcoxon test was statistically significant pre-post educational program (Z − 4,876, p < 0.001) with an increase from 70% to 83.3% of correct answers after the educational program and a satisfaction of 87.09%. Conclusion: A brief educational program, implemented in a cancer hospital during the pandemic, is effective in increasing health literacy and is highly valued by the participants. © 2022

A Digital Transformation Journey for a Mature using Production Technologies and Innovation Principles

A novel solution was proposed in Ecuador to transition from reactive to a proactive way of working into a collaborative environment. This new workflow is supported by a portfolio of three production technologies that integrates live and historical information by combining the edge intelligence strength (for each production element connected to IoT platform) and the cloud insight to enhance the field operational efficiency. Technology that reduces carbon footprint and increases people's efficiency through automation of repetitive tasks. The main challenge that required an integrated and smart solution was the existence of silos, meaning that all production chain elements were disconnected. The solution consisted of a portfolio of three technologies. First, connecting all production chain elements to one unique gateway and Edge platform: all data were consolidated to perform asset surveillance, monitoring, and controlling of electrical submersible pump (ESP) parameters from any vendor. Second, creation of an autonomous system aiming to avoid gas blockage on ESPs. Third, deployment of Production Engineering Orchestrator, fully completed and in continuous improvement, easing collaborative, day-to-day analysis for production, operations, and exploitation engineers We achieved remarkable results with Internet of Things (IoT) and cloud insights implementation;for instance, travel reduction of 18%, personnel efficiency increase (production operations 7% and surveillance engineers 25%), 47% events detection increase, 32% well uptime increase, and 2.14 t carbon dioxide emissions reduction (22.6%). Because of the outstanding results achieved from IoT adoption, new applications were deployed in other projects. With automated annular gas handling, production challenges related to high gas/oil ratio wells were solved. Solution consisted in delivering an automated ESP gas-handling process by using a securely connected, solar-powered skid to optimize well performance, production was increased by 12%, field visits reduced by 94%, and valves manipulation decreased by 97%. Other applications are also running in parallel, to expand the concept of intelligent asset solution. For the production engineering workflows orchestrator, the native implementation is completed, where the highest business impact workflows are included, such as smart production surveillance, waterflooding optimization and ESP surveillance. Insights are shown in "production overview". It is also possible to follow up oil and water producing wells, task modules, customized maps and graphs, sanity check processes, and well model calibration (including the paraffin curves). The integration of these three digital production technologies to improve artificial lift surveillance, production surveillance, and waterflooding optimization workflows is already deployed and showing tangible benefits. Currently, a mature field project is currently working in a collaborative environment, promoting a new proactive operational philosophy that avoids early pump failures, reduces downtime, field trips, personnel exposure due to the COVID-19 pandemic and supports the environmental commitment towards the carbon footprint reduction. Copyright © 2022, Society of Petroleum Engineers.

Bibliometric Software: The Most Commonly Used in Research

Scientific research allows for increasing the knowledge of reality and the phenomena that manifest and evolve in it. Today, research is considered a professional competence, which is mainly developed in university institutions. Day by day, the so-called information society is flooded with research works of all types and qualities. At the same time, there is an increase in the number of annual publications that analyze data and measure intellectual works and their contribution to the scientific heritage of each discipline. A series of indicators are generated based on various parameters such as authors, type of document, language, and keywords, among others. The visualization of these numerous indicators, which vary over time, can be achieved effectively through the use of bibliometric software, which is also renewed in its functionality and features. The following is a study, assisted by systematic and bibliometric review techniques, with the aim of identifying the most widely used bibliometric software and those emerging that serve as a guide and good practice in new bibliometric research to obtain notable and relevant knowledge. The applications "VOSviewer", "CiteSpace" and "Bibliometrix" stand out and tools such as "Scopus API R code", "Covidence", "HistCite", "BICOMB", "EndNote X9.6 Statistical", "Ucinet 6.0", "Tools for Innovation Monitoring", "Profiles Research Networking Software", among others, emerge. © 2022 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).

Effect of COVID-19 control measures on other respiratory transmitted diseases

Introduction: Measures to control COVID-19 epidemic are likely to enable the control of other respiratory transmitted diseases.

Effect of COVID-19 Control Measures on Other Respiratory Transmitted

Introduction: Measures to control COVID-19 epidemic are likely to enable the control of other respiratory transmitted diseases. Objective: To determine the effect of the measures applied for the prevention and control of COVID-19 on the incidence of other respiratory transmitted diseases. Methods: An ecological time series study was carried out. The units of analysis were the time series of the weekly incidence of the cases treated for some infectious diseases (acute respiratory infections, chickenpox, scarlet fever, and viral meningitis) from 2013 to 2020 in Santiago de Cuba. These units were used to create the endemic channels by the infra-maximal and supra-minimal method with series from the 52 weeks between 2013 and 2019, which served as the starting point for the analysis of the 2020 series. Results: The increase of some respiratory diseases in 2020 coincided with the increase of COVID-19 epidemic in the territory, and from week 15 onwards, it was evidenced a decrease in the incidence which is consistent with the date on which COVID-19 control measures were established (movement restriction, mask wearing, hand washing and disinfection, social distancing, etc.). Conclusions: Control measures for COVID-19 have exerted a positive impact on the incidence of the selected diseases, which exhibited a reduction below what was expected for 2020 in Santiago de Cuba. © 2022, Editorial Ciencias Medicas. All rights reserved.

Incidencia, Características y Evolución de las Endocarditis Nosocomiales Durante la Pandemia COVID-19

Introducción: La pandemia COVID-19 ha podido tener influencia en la incidencia de endocarditis infecciosa nosocomial (EIN). Objetivos: Describir la incidencia, características y evolución de la EIN durante la pandemia COVID-19. Material y métodos: Estudio retrospectivo unicéntrico incluyendo las EIN definidas, según los criterios de Duke, desde marzo 2020 hasta marzo 2021. Se dividieron a los pacientes en ingreso por COVID-19 (grupo COVID) o por otros motivos (grupo no COVID). Se comparó la incidencia de EIN con el mismo periodo de 2019-2020. Resultados: Durante el periodo de estudio se diagnosticaron 22 EIN, 7 (31,8%) en COVID, 15 (68,2%) en no COVID. La incidencia fue 9,7 casos/10.000 ingresos (22/22.596). La incidencia en el mismo periodo 2019-2020 fue 4,6/10.000 (10/21.668), siendo la diferencia significativa (OR 1,91, IC95% 1,03-3,96, p = 0,038). Durante el periodo 2020-2021, la incidencia de EIN en COVID fue 24,6/10.000 (7/2.846) frente a 7,5/10.000 (15/19.750) en no COVID, siendo la diferencia significativa (OR 3,23 IC95% 1,32-7,95, p < 0,001). La mediana de edad fue 75 años (RIQ 68-80), siendo varones 68,2%. La mediana de Índice de Charlson fue 5 (RIQ 4-6). Un 36,4% presentaban válvula protésica, mientras un 22,7% valvulopatías significativa no protésica. Los pacientes COVID habían recibido más frecuentemente inmunosupresores (71,4% vs. 13,3%, p = 0,014), sin otras diferencias entre grupos. El foco primario fue considerado vascular en 86,4% (19/22;10 por vía periférica (VP), 5 por catéter venoso central (CVC), 4 no se pudo diferenciar origen entre VP o CVC). 3 pacientes presentaron foco no vascular (1 genitourinario, 2 gastrointestinal). No hubo diferencias entre grupos. Las manifestaciones fueron: fiebre 95,5%;insuficiencia cardiaca 68,2%;embolismos 45,5%;ictus 40,9%;insuficiencia renal 40,9%;bacteriemia persistente 38,1%;y shock séptico 14,3%. Los pacientes no COVID presentaron con más frecuencia clínica subaguda (0 vs. 46,7%, p = 0,042), sin otras diferencias estadísticamente significativas. La etiología fue: estafilococos coagulasa negativo 6 (27,3%);Enterococcus faecalis 6 (27,3%);Staphylococcus aureus 4 (18,2%);Candida albicans 3 (13,6%). En 3 casos no hubo aislamiento microbiológico (13.6%). No hubo diferencias entre grupos. La mortalidad a 30 días fue 45,5%, siendo la EIN o sus complicaciones la causa en todos los casos salvo 1 (no COVID). No hubo diferencias de mortalidad entre grupos (28,6% vs. 53,3%, p = 0,381). Conclusiones: La incidencia de EIN ha aumentado durante la pandemia, especialmente en pacientes ingresados por COVID-19. El foco primario de las EIN fue predominantemente vascular. Afectaron frecuentemente a pacientes con comorbilidad y patología valvular previa. Las manifestaciones, etiología y evolución fueron similares en COVID y no COVID, destacando una elevada frecuencia de eventos embólicos, especialmente ictus. Las EIN asocian elevada morbimortalidad y es importante extremar las medidas de prevención.

Survey on medical care of patients with epilepsy during the coronavirus pandemic

Introduction: The coronavirus 2019 pandemic represented a great challenge for the health system. The demand for hospital beds and resources for the treatment of the coronavirus has forced the health service to reorganize and the National Government to implement strict measures to reduce the rate of infections. Objective: The objective of the study was to determine whether the care and access to medication of patients with epilepsy was affected during mandatory quarantine. Materials and methods: This is a cross-sectional study that was conducted in two medical health centers, one public and one private, in the Autonomous City of Buenos Aires, Argentina. A survey was designed in the Google Forms platform and sent by email between April and June 2020 to patients with epilepsy treated in both institutions. Questions on demographic characteristics, access to the health care system and changes in the frequency of seizures were included. Results: 488 patients were contacted, obtaining a response of 50.8%. Regarding the health care coverage, 36.5% of the patients did not have any. 49.1% had problems accessing to the medications. 29.7% of the patients contacted referred an increase in the frequency of seizures. The main contact method used was email (35%) and telephone (15.4%). 58% obtained their prescriptions by alternative methods while 13% reported not having access to them. Conclusions: Our results reflect the importance of incorporating alternative means of communication in special situations to guarantee the care and treatment of patients with chronic diseases.

Cerebrovascular Manifestations of COVID-19 in Young Adults

Objective: The aim of this study was to characterize patients hospitalized with COVID-19 and cerebrovascular disease, with a focus on young patients diagnosed with CVST and ICH/SAH. Background: There have been many reported neurologic manifestations of coronavirus disease 2019 (COVID-19) including cerebrovascular events such as ischemic stroke, hemorrhagic stroke including intracerebral hemorrhage/subarachnoid hemorrhage (ICH/SAH) and central venous sinus thrombosis (CVST). However, there has not been much focus on this topic in young adults aged under 50. Design/Methods: Retrospective chart review was used to obtain parameters of patients hospitalized in Chicago area hospitals with COVID-19 and a neurologic diagnosis including acute ischemic stroke, subarachnoid hemorrhage, intracranial hemorrhage, and cerebral venous sinus thrombosis. Data including patients' comorbidities and disease course was entered into a secure database by representatives from 4 different tertiary care centers. Results: A total of 27 patients aged 18 to 50 were hospitalized in Chicago land tertiary care centers from March 30, 2020 to February 1, 2021 with cerebrovascular disease and concurrently tested positive for COVID-19. Of these patients, 2 were found to have venous sinus thrombosis. 9 patients had hemorrhagic strokes, of these, 4 patients with ICH were thought to have had spontaneous hemorrhages. 9 of 27 patients had no past medical history. Conclusions: This population had a large portion, 11 out of 27 patients, with non-ischemic cerebrovascular insults such as CVST, ICH, or SAH while concurrently infected with COVID-19. Unlike most classic patients who develop these conditions, our population did not have traditional risk factors such as smoking or hypertension. Systemic inflammation, hypoxia, platelet dysfunction, or hyper-coagulability due to COVID-19 are theorized as the cause of these cerebrovascular manifestations in the absence of traditional risk factors. Spontaneous cerebrovascular manifestations of COVID-19 continue to be investigated, particularly in younger patients without traditional risk factors.

[Anti-SARS-CoV-2 seroprevalence in administrative staff of the Mexican Institute for Social Security]

Background: Asymptomatic subjects, the lack of diagnostic tests and, in countries like Mexico, the epidemiological surveillance method does not allow to establish the real number of infections in the COVID-19 pandemic. Frontline health personnel, as well as other groups related to priority activities are considered of high risk. We included administrative workers in contact with health personnel in the hospital units of the Mexican Institute for Social Security (IMSS, according to its initials in Spanish). Objective: To identify the seroprevalence of antibodies to SARS-CoV-2 in IMSS' administrative staff who does not treat patients. Material and methods: 76 volunteer participating individuals were incluided;IgG antibodies against the SARS-CoV-2 nucleoprotein were measured. A questionnaire was administered to the participants in order to identify possible risk factors. Results: 76 participants were included (39 men, 51.7%), with a median age of 42 years. 29 out of 76 subjects (38.2%), whose median age was 38 years (range 18-69 years);15 men (51.7%), and 14 women (48.3%). A higher percentage of positive subjects under 45 years of age (n = 20, 84.2%) was observed than those aged 45 or over (n = 9, 25%), with an OR of 3 (95% CI 1.13-7.96, p = 0.03). No statistically significant difference was found regarding the type of comorbidity. Conclusions: The prevalence identified shows an important circulation of the virus in the administrative staff.